Status:
COMPLETED
Fractalkine, a CX3C Chemokine, Act as a Mediator of Ocular Angiogenesis
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Proliferative Diabetic Retinopathy
Angiogenesis
Eligibility:
All Genders
Brief Summary
Fractalkine (FKN) is a chemoattractant and adhesion molecule for leukocytes. Angiogenic effect of FKN also has been reported. We investigate FKN-mediated angiogenesis in ocular angiogenic disorders.
Detailed Description
Fractalkine (FKN), the sole member of the CX3C chemokine family, is named for its fractal geometry. The CX3C motif, with three amino acids between the two terminal cysteines, makes fractalkine distinc...
Eligibility Criteria
Inclusion
- clinical diagnosis of proliferative diabetic retinopathy.
- who will receive vitrectomy for treatment of disease.
Exclusion
- previous ocular surgical history.
- history of uveitis
- history of ocular trauma.
Key Trial Info
Start Date :
January 1 1998
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 1998
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00728598
Start Date
January 1 1998
End Date
December 1 1998
Last Update
August 6 2008
Active Locations (1)
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1
The department of ophthalmology, National Taiwan University Hospital
Taipei, Taiwan