Status:
COMPLETED
Biomarker for Peritoneal Ultrafiltration Failure
Lead Sponsor:
Sun Yat-sen University
Conditions:
Continuous Ambulatory Peritoneal Dialysis
Eligibility:
All Genders
20-65 years
Brief Summary
This study will examine the peritoneal tissue, serum and dialysate proteins of peritoneal dialysis (PD) patients with different types of peritoneal solute transport by differential proteomics techniqu...
Detailed Description
Ultrafiltration failure (UFF) is an important cause of technical failure in PD patients. It may develop over time and is, therefore, especially important in longterm PD. However, the study on UFF is v...
Eligibility Criteria
Inclusion
- Continuous ambulatory peritoneal dialysis patients whose primary disease is chronic glomerulonephritis, The range of age is 20 to 65 year old.
- serum albumin level ≥ 35 g/L.
- Residual GFR ≥ 2 ml/min/1.73 m2.
- 500 ml/d ≤ urine output ≤ 1000 ml/d.
- Subjects who agree to participate in the study and sign the informed consent.
Exclusion
- Patients who are secondary nephropathy.
- Patients with congestive heart failure, angina, myocardial infarction, severe valvular heart disease, malignant hypertension, hypertensive encephalopathy or cerebrovascular accident.
- Patients with chronic liver disease, dyscrasia, psychiatric disorder, alcohol or drug abuse.
Key Trial Info
Start Date :
October 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00728806
Start Date
October 1 2007
End Date
December 1 2011
Last Update
May 22 2015
Active Locations (1)
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1
The 1st Affiliated Hospital, Sun Yet-sen University
Guangzhou, Guangdong, China, 510080