Status:
COMPLETED
Peripherally Inserted Central Catheter (PICC) Thrombosis: Reverse Taper Versus Non-tapered Catheters
Lead Sponsor:
University of Pennsylvania
Conditions:
Venous Thrombosis
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The purpose of this study is to compare two different marketed PICC (peripherally inserted central catheter) designs. Clotting rates, procedural bleeding and ease of catheter insertion will be compare...
Eligibility Criteria
Inclusion
- All inpatients, age 18 to 90, in need of de novo central venous access with a double lumen catheter indication of \> 2 weeks
- Informed consent and HIPAA consent forms discussed and signed by patient or their authorized representative
Exclusion
- Skin related problems around the insertion site (infection, phlebitis, scars)
- History of mastectomy/axillary dissection on insertion side
- Coagulopathy with an INR of \> 2.0
- Thrombocytopenia with platelets \< 25,000 uL
- Renal insufficiency with a creatinine of \> 3.0 mg/dL
- Documented current upper extremity or central venous thrombosis
- Hypercoagulable states (protein C or S deficiency, AT-III deficiency, lupus anticoagulant)
- Catheters needed for therapy within less than an hour (emergent placement not allowing sufficient time for proper research consent and randomization)
- Patient has already been enrolled in this research study
- Life expectancy less than 1 month
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
339 Patients enrolled
Trial Details
Trial ID
NCT00728819
Start Date
August 1 2008
End Date
August 1 2011
Last Update
April 27 2018
Active Locations (1)
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1
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104