Status:
COMPLETED
The Efficacy, Safety and Genetic Polymorphism of Hypoca and Adalat OROS in Hypertensive Patients
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Hypertension
Eligibility:
All Genders
22-87 years
Brief Summary
Nifedipine and barnidipine act as calcium channel blockers, and are widely prescribed for pressure control of prehypertension and stage 1 hypertension. CYP3A4 is responsible for the metabolism of nif...
Detailed Description
For each drug, 20 patients will be enrolled. Patients' blood pressure and heart rates will be measured at first visit, followed by visits at week4 , week 8 and week 12. Blood samples will be drawn at ...
Eligibility Criteria
Inclusion
- 20\~90 years old patient
- mild to moderate hypertensive patients
- can finish this study
- can sign agreement
Exclusion
- severe hypertension
- Heart failure, Arrhythmia
- Liver or kidney failure
- pregnant women
- allergy to dihydropyridines
- attend other clinical trials in past 3 month
Key Trial Info
Start Date :
April 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2007
Estimated Enrollment :
43 Patients enrolled
Trial Details
Trial ID
NCT00728858
Start Date
April 1 2006
End Date
February 1 2007
Last Update
August 6 2008
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