Status:
COMPLETED
Gait Patterns After Intraarticular Treatment of Patients With Osteoarthritis of the Knee
Lead Sponsor:
Philipps University Marburg
Collaborating Sponsors:
University Hospital Muenster
Conditions:
Osteoarthritis
Eligibility:
All Genders
35-80 years
Phase:
PHASE4
Brief Summary
The aim of this study was to analyse the difference of the functional and clinical outcome after intraarticular treatment of patients with osteoarthritis of the knee with a single injection of hyaluro...
Detailed Description
Osteoarthritis (OA) is the most common chronic joint disease of the aging patient. The primarily affected joints are the knee and hip. The progress of the disease has an important influence on the pat...
Eligibility Criteria
Inclusion
- men and women between 35 and 80 years of age
- radiographically verified degenerative osteoarthritis of the knee (grade II or III according to the Kellgren and Lawrence classification)
- pain of at least 40 mm on a 100 mm visual analogue scale (VAS) at initial examination
- persisting pain for at least 6 months
- Lequesne-Score of at least 10 points
- good physical and mental status
- good compliance and agreement to participate in this study
Exclusion
- non-degeneratively induced osteoarthritis
- rheumatoid arthritis
- ligamentous instability or complete resection of the meniscus
- Sudeck´s disease
- operations of the affected knee within the last three months
- varus or valgus deformity of more than 15 degrees
- patellofemoral arthritis
- intraarticular therapy of the affected joint within the last 6 months with hyaluronan and three months with glucocorticoids
- severe systemic diseases (tumor, exacerbated diabetes mellitus, hyperthyroidism)
- anti-thrombotic medication or regular medication with NSAID/psychiatric pharmaceuticals
- infectious diseases
- alcohol abuse
- drugs
- psychiatric diseases or suicidal tendencies
- involvement in another study
- non-compliance
- acute hemarthrosis or joint effusion
- allergic predisposition
- skin infections or skin diseases around the knee
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2005
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00731289
Start Date
July 1 2003
End Date
December 1 2005
Last Update
August 8 2008
Active Locations (1)
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1
Department of Orthopaedics, Movement Analysis Lab, University Hospital Münster, Germany
Münster, Germany, 48149