Status:
COMPLETED
Compression Device Safety Study on Edema
Lead Sponsor:
ConvaTec Inc.
Collaborating Sponsors:
Bristol-Myers Squibb
Conditions:
Edema
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
To evaluate the safety of the prototype Compression Device in subjects with Oedema
Eligibility Criteria
Inclusion
- Subjects aged between 18 and 80, willing and able to provide written informed consent, and able to wear the device and follow the requirements of the protocol
- Subjects who have an ankle to brachial pressure index (ABPI) of at least 0.8.
- Subjects who suffer from chronic oedema (i.e. CEAP classification of C3, C4 or C5 1.)
- Subjects who have Chronic Venous Insufficiency (CVI), which has been present for 6 weeks or longer and who have refluxes \>0.5 sec in one or more major venous segments, superficial or deep or both (CEAP classification: C3-C5 1.; Ep,s; As,d; Pr).
Exclusion
- Subjects with a history of skin sensitivity to any of the components of the study product.
- Subjects who have previously been entered into the study before
- Subjects who have a history of Deep Vein Thrombosis (DVT) within the last 6 months
- Subjects who have an active leg ulcer (i.e. CEAP classification of C6 1).
- Subjects with active cardiac disease or significant history of cardiac disease (including history of myocardial infarction, heart failure, valvular disease, arrhythmia and those with a pacemaker or have previously had a pacemaker).
- Subjects who have initiated treatment or changed the dose within the past month of pharmaceutical agents that reduce clotting e.g. aspirin (except low-dose aspirin), anti-platelets, anti-coagulants and coumarin.
- Subjects who are currently taking pharmaceutical agents that can modify the amount of leg oedema (e.g., diuretics, dihydropyridine calcium channel blockers, phlebotonic drugs, or fluctuating doses of systemic steroids) or have taken these agents within the last 10 days.
- Subjects who are pregnant
- Subjects who have worn compression therapy in the last 48 hours
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2004
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00732719
Start Date
October 1 2004
End Date
December 1 2004
Last Update
October 31 2008
Active Locations (1)
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1
Hautarzt Phlebologe Allergologe
Freiburg im Breisgau, Germany