Status:
COMPLETED
Nebulized Budesonide for Children Who Are Hospitalized for Acute Wheezing
Lead Sponsor:
Kecioren Education and Training Hospital
Conditions:
Asthma
Acute Asthma
Eligibility:
All Genders
6-6 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in children who have hospitalized for acute wh...
Detailed Description
Context: Inhaled steroids reduced admission rates in patients with acute asthma, but it is unclear if there is a benefit of inhaled corticosteroids when used in addition to systemic corticosteroids. T...
Eligibility Criteria
Inclusion
- Children who have recurrent wheezing attacks
- Children who admitted to the hospital for acute wheezing
- Clinical asthma score of 3-9
- Parental/guardian permission (informed consent) and if appropriate, child assent
Exclusion
- Systemic corticosteroid use in the last 30 days
- Chronic lung diseases including cystic fibrosis
- Immunodeficiency
- Cardiac disease requiring surgery or medications
- Adverse drug reaction or allergy to budesonide, albuterol, ipratropium bromide, prednisone, prednisolone, or methylprednisolone
- Known renal or hepatic dysfunction
- Impending respiratory failure requiring positive pressure ventilation
- Immune deficiency
- Gastroesophageal reflux disease
- Suspected foreign body aspiration or croup
- Anatomic abnormalities of the respiratory tract
Key Trial Info
Start Date :
September 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2010
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00733473
Start Date
September 1 2007
End Date
January 1 2010
Last Update
December 20 2011
Active Locations (1)
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1
Kecioren Education and Training Hospital
Ankara, Kecioren, Turkey (Türkiye), 06380