Status:
COMPLETED
Memory and Picture Viewing Study
Lead Sponsor:
Duke University
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Healthy
Brain Reactivity of Non-smokers Undergoing fMRI Scanning
Eligibility:
All Genders
18-55 years
Brief Summary
The purpose of this study is to obtain a database of brain function from a sample of non-smokers while they do tasks in an MRI (magnetic resonance imaging) machine. Our hypothesis is that among nonsmo...
Detailed Description
Thirty six non-smokers will undergo functional magnetic resonance imaging (fMRI) scanning. During scanning participants will complete the n-back task-a measure of working memory-and the cue-reactivity...
Eligibility Criteria
Inclusion
- generally healthy
- right-handed non-smokers
- between the ages of 18-55
- an expired CO concentration of 5 ppm or less; or a negative urine cotinine test of 100 ng/mL or less (to confirm a non-smoker)
- having smoked \< 50 cigarettes in their lifetime
Exclusion
- inability to attend all sessions
- significant health problems (hypertension, emphysema, seizure disorder, history of significant heart problems)
- use of psychoactive medications
- use of any tobacco or nicotine containing products
- current alcohol or drug abuse
- use of illegal drugs as measure by a urine drug screen
- presence of conditions that would make MRI unsafe (pacemaker, metallic implants
Key Trial Info
Start Date :
July 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT00736203
Start Date
July 1 2008
End Date
November 1 2011
Last Update
February 7 2013
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27705