Status:

TERMINATED

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

Lead Sponsor:

Duke University

Conditions:

Fatty Liver

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to find out if Metformin is safe and useful in the treatment of NAFLD.

Detailed Description

NAFLD is a poorly understood disease which may cause an enlarged liver, abnormal liver test results, and scarring of the liver. It may occur more often in people with obesity, high levels of cholester...

Eligibility Criteria

Inclusion

  • biopsy-proven NAFLD, determined within 12 months of study initiation

Exclusion

  • \> 20 grams of alcohol/day
  • impaired oral glucose tolerance test
  • known diagnosis of diabetes mellitus
  • hepatitis C infection
  • cirrhosis

Key Trial Info

Start Date :

April 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT00736385

Start Date

April 1 2009

End Date

December 1 2012

Last Update

January 26 2024

Active Locations (1)

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1

Duke University Medical Center

Durham, North Carolina, United States, 27710