Status:

COMPLETED

Proximal Femoral Nail Antirotation™ (PFNA) Versus Gamma Nail 3™ (Gamma3) for Intramedullary Nailing of Unstable Trochanteric Fractures

Lead Sponsor:

AO Clinical Investigation and Publishing Documentation

Collaborating Sponsors:

Synthes Inc.

Conditions:

Unstable Trochanteric Fractures

Eligibility:

All Genders

55+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare rates of any fracture fixation complication and revision rates after intramedullary fixation of unstable trochanteric fractures between the Proximal Femoral Nai...

Detailed Description

Intramedullary nailing of unstable per- and subtrochanteric femoral fractures is a standard procedure in trauma and orthopaedic surgery. Unstable fractures treated with intramedullary nailing carry th...

Eligibility Criteria

Inclusion

  • Age 55 years and more
  • Patients with isolated, unstable, closed or type 1 open trochanteric fractures, classified as AO 31-A2 or AO 31-A3
  • Definitive primary fracture treatment with PFNA or Gamma3 (defined inTable 1) within three days after the index event
  • Signed written informed consent (by the subjects or legal guardian) and agreement to attend the planned follow-ups

Exclusion

  • Pathologic fracture of any other cause than osteoporosis
  • Patients or legal guardian refusing to sign the informed consent form
  • Multiple trauma
  • Type 2 and 3 open fractures
  • Drug or alcohol abuse
  • Wound and/or bone healing disorders of any other cause than diabetes mellitus or smoking
  • Active malignancy
  • Expected life expectancy ≤ 3 months
  • Inability to walk independently prior to injury event (use of one stick is allowed. Not meeting inclusion criteria are bedridden, wheel-chair ridden and walker dependent subjects)
  • Neurological and psychiatric disorders that would preclude reliable assessment (eg,, Parkinson disease, Multiple sclerosis, severe depression)
  • Rheumatoid arthritis

Key Trial Info

Start Date :

November 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2010

Estimated Enrollment :

440 Patients enrolled

Trial Details

Trial ID

NCT00736684

Start Date

November 1 2007

End Date

September 1 2010

Last Update

February 11 2011

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Hospital Universitario "Marqués de Valdecilla"

Santander, Cantabria, Spain, 39008

2

Hospital Clinic

Barcelona, Catalonia, Spain, 08036

3

Hospital Gregorio Marañon

Madrid, Madrid, Spain, 28007

4

Hospital Puerta de Hierro

Madrid, Madrid, Spain, 28035