Status:
TERMINATED
Assess Safety, Tolerability and Pharmacokinetic (PK) of AZD1704 in Healthy Japanese Male and Non-Fertile Female Volunteers
Lead Sponsor:
AstraZeneca
Conditions:
Healthy Volunteers
Eligibility:
All Genders
20-45 years
Phase:
PHASE1
Brief Summary
The primary objective of this study is to investigate the safety and tolerability of AZD1704 following single ascending doses in healthy Japanese male and non-fertile female volunteers by assessment o...
Eligibility Criteria
Inclusion
- Healthy Japanese males and non-fertile females, defined as first generation Japanese (both parents and grandparents are of Japanese origin, the subject is born in Japan and has not been living outside of Japan for more than 5 years) aged 20-45 years .
- Clinical normal physical findings
- BMI 19 - 27, weight 50 - 95 kg
Exclusion
- History of somatic disease/condition or ongoing psychiatric disease/condition that may interfere with the objectives of the study.
- History of psychotic disorder among first-degree relatives.
- History of use of antipsychotic, antidepressant or anxiolytic drugs, prescribed as well as non-prescribed use.
- Smoking more than 7 cigarettes per week or consumption of more than 3 portion of snuff or equivalent per day within 30 days before administration of study drug.
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00736788
Start Date
August 1 2008
End Date
September 1 2008
Last Update
December 10 2010
Active Locations (1)
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1
Research Site
London, United Kingdom