Status:
COMPLETED
Oxaliplatin and 5-Fluorouracil With or Without Docetaxel in Elderly Patients (>65 y) With Stomach and Esophagus Cancer
Lead Sponsor:
Krankenhaus Nordwest
Conditions:
Gastric Cancer
Adenocarcinoma of the Esophagogastric Junction
Eligibility:
All Genders
65+ years
Phase:
PHASE2
Brief Summary
In this trial, FLOT will be evaluated as therapy option for elderly patients (\>65 years) with advanced gastric cancer in comparison to the well established FLO scheme. The hypothesis is that FLOT is ...
Detailed Description
Patients with locally advanced, potentially operable or metastatic gastric cancer or adenocarcinoma of the esophagogastric junction without prior therapy in the palliative setting are treated with: *...
Eligibility Criteria
Inclusion
- metastatic or locally advanced gastric cancer or adenocarcinoma of the esophagogastric junction
- no prior chemotherapy in metastatic state
- adequate blood and biochemistry parameters
Exclusion
- hypersensitivity for 5-FU, Leucovorin, Oxaliplatin or Docetaxel
- KHK, cardiomyopathy or cardiac insufficiency
- malignancy \<5 years ago
- brain metastases
- severe internal disease or inadequate blood and biochemistry parameters
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
143 Patients enrolled
Trial Details
Trial ID
NCT00737373
Start Date
August 1 2007
End Date
March 1 2011
Last Update
September 19 2012
Active Locations (1)
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1
Krankenhaus Nordwest
Frankfurt, Germany, 60488