Status:

COMPLETED

The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris

Lead Sponsor:

University of Edinburgh

Conditions:

Coronary Heart Disease

Angina Pectoris

Eligibility:

All Genders

Brief Summary

The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.

Detailed Description

Air pollution is a major cause of cardiovascular morbidity and mortality. The mechanism and components of air pollution responsible for these cardiovascular effects are unknown but small combustion-de...

Eligibility Criteria

Inclusion

  • Documented coronary heart disease
  • Symptoms of stable angina pectoris

Exclusion

  • History of arrhythmia
  • Severe 3 vessel coronary artery disease or left main stem stenosis that has not been revascularised
  • Resting conduction abnormality
  • Digoxin therapy
  • Uncontrolled hypertension
  • Renal or hepatic failure
  • Patients with unstable disease (ACS or unstable symptoms within 3 months)
  • Asthma
  • Intercurrent illness

Key Trial Info

Start Date :

August 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT00737958

Start Date

August 1 2008

End Date

December 1 2008

Last Update

March 31 2010

Active Locations (1)

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University of Edinburgh

Edinburgh, Midlothian, United Kingdom, EH16 4SB