Status:
TERMINATED
Effects of Ambient Air Pollution Exposure in Patients With Stable Angina Pectoris During Normal Daily Activities
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
Imperial College London
Conditions:
Angina Pectoris
Coronary Heart Disease
Eligibility:
All Genders
Brief Summary
The purpose of this study is to identify whether exposure to ambient levels of air pollution during normal daily activities has a functional impact on patients with coronary heart disease
Detailed Description
Exposure to air pollution has been shown in epidemiological studies to be closely linked to cardiovascular morbidity and mortality. The exact components of air pollution that underlie the cardiovascul...
Eligibility Criteria
Inclusion
- Documented coronary artery disease
- Symptoms of stable angina pectoris
- Positive BRUCE exercise stress test between 3 and 13 minutes
Exclusion
- History of arrhythmia
- Severe 3 vessel coronary disease or left main stem stenosis that has not been revascularised
- Resting conduction abnormality
- Digoxin therapy
- Uncontrolled hypertension
- Renal or hepatic failure
- Unstable symptoms or acute coronary syndrome within 3 months
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT00738491
Start Date
August 1 2008
End Date
August 1 2013
Last Update
December 2 2014
Active Locations (2)
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1
University of Edinburgh
Edinburgh, Midlothian, United Kingdom, EH16 4SB
2
Imperial College
London, United Kingdom, SW3 6LY