Status:
COMPLETED
Evaluating the Effects of Hormone Replacement Therapy on Brain Function (The WHIMS-MRI Study)
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsors:
Wake Forest University Health Sciences
Conditions:
Stroke
Eligibility:
FEMALE
65-90 years
Brief Summary
A silent stroke is a type of stroke that does not produce any severe symptoms, but may slightly affect memory or thinking abilities. Women who take hormone replacement therapy (HRT) may have a higher ...
Detailed Description
A silent stroke is a type of stroke that occurs as a result of blockage in the small blood vessels in the brain. Older adults, in particular, are at risk for silent strokes. This type of stroke does n...
Eligibility Criteria
Inclusion
- Participated in the WHIMS study
- Receives medical care at 1 of the 13 WHIMS MRI clinics
Exclusion
- Currently has a pacemaker (either working or non-functioning), intracranial aneurysm clip, neurostimulator, defibrillator, intra-ocular ferrous foreign body (e.g., metal in the eye), or Harrington rods
- Currently has a magnetically or electrically activated device, including any of the following items: cochlear implant, transcutaneous electrical nerve stimulation (TENS) unit, implanted pump (insulin or infusion), or a McGee Stapes implant
- Potential participants who have the following exclusion criteria may be eligible for participation, based on study staff approval:
- Metal fragments around critical soft tissue (i.e., shrapnel near spinal cord)
- Prosthetics
- Eyelid spring or wire
- Metallic stent, filter, or coil
- Breast tissue expander
- Tattoo or non-removable body piercing
- Difficulty lying flat
- Difficulty breathing
- Claustrophobia
Key Trial Info
Start Date :
May 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2007
Estimated Enrollment :
1426 Patients enrolled
Trial Details
Trial ID
NCT00739869
Start Date
May 1 2004
End Date
March 1 2007
Last Update
May 6 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157