Status:

COMPLETED

Molecular Features Predicting Response/Resistance to Trastuzumab in Metastatic Breast Cancer Patients

Lead Sponsor:

Istituto Clinico Humanitas

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

Aim of the study is to assess the impact on response to Herceptin-based therapy in patients with advanced breast cancer. Tumor specimens from primary breast cancer will be analized for several biologi...

Eligibility Criteria

Inclusion

  • Hystological diagnosis of breast cancer
  • Availability of tumor tissue
  • Availability to assess the response to Trastuzumab according to RECIST criteria
  • Availability of clinical data

Exclusion

  • Unavailability of tumor tissue
  • Impossibility to assess the response to Trastuzumab according to RECIST criteria

Key Trial Info

Start Date :

October 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2010

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT00740532

Start Date

October 1 2007

End Date

August 1 2010

Last Update

September 2 2010

Active Locations (1)

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Istituto Clinico Humanitas

Rozzano, Milan, Italy, 20089