Status:
COMPLETED
A Crossover Study of the Acute Effects of Olanzapine in Healthy Volunteers
Lead Sponsor:
Milton S. Hershey Medical Center
Collaborating Sponsors:
American Medical Association
Conditions:
Insulin Resistance
Diabetes Mellitus
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
The purpose of this clinical research study is to examine the acute hormonal and metabolic effects of the drug olanzapine, as well as appetite effects, in healthy volunteers. The hypotheses to be test...
Eligibility Criteria
Inclusion
- Healthy Volunteer
- Body Mass Index of 18.5-25 kilograms per square meter
- Must be able to swallow tablets
- Able to give informed consent
Exclusion
- Any DSM-IV TR Axis I psychiatric disorder (except nicotine dependence)
- Presence of any medical disorder that may confound the assessment of relevant biologic measures, including: significant organ system dysfunction, metabolic diseases, type 1 diabetes mellitus, type 2 diabetes mellitus, pregnancy, endocrine disease, coagulopathy, clinically significant anemia, or acute infection
- Subjects who have taken any antipsychotic medication within the last 6 months
- Personal or family history of seizures and/or cardiac arrhythmias
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2011
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00741026
Start Date
August 1 2008
End Date
May 1 2011
Last Update
July 14 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Penn State College of Medicine, Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, United States, 17033