Status:

COMPLETED

The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution

Lead Sponsor:

The Hospital for Sick Children

Conditions:

Hypertension

Congestive Cardiomyopathy

Eligibility:

All Genders

2-5 years

Phase:

PHASE3

Brief Summary

The primary objective of this study is to study the acute effects of angiotensin-converting enzyme inhibitor (ACEI) on systemic, pulmonary and cerebral blood flow in post bidirectional cavopulmonary c...

Detailed Description

The intermediate stage of the bi-directional cavopulmonary connection (BCPC) in the management algorithm of single ventricle palliation is a unique and extraordinary physiologic condition. It places t...

Eligibility Criteria

Inclusion

  • BCPC patients at time of routine pre-Fontan catheterization
  • Patients between the ages of 2 months and 5 years old

Exclusion

  • Patients who have had ACEI therapy within 24 hours of the procedure

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00741156

Start Date

July 1 2008

End Date

January 1 2010

Last Update

December 18 2015

Active Locations (1)

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1

The Hospital for Sick Children

Toronto, Ontario, Canada