Status:

COMPLETED

Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administration of Magnevist

Lead Sponsor:

Bayer

Conditions:

Fibrosis

Kidney Failure

Eligibility:

All Genders

2+ years

Brief Summary

Assess potential risk for NSF in subjects with renal impairment (moderate) post magnevist injection. Subjects will be screened within 48 hours of previously scheduled MRI, those meeting the enrollment...

Eligibility Criteria

Inclusion

  • Patients must have moderate (eGFR 30-59 ml/min/1.73 m\^2) renal impairment and be scheduled for a contrast enhanced MRI with Magnevist Injection at the recommended dose of 0.1 mmol/kg.

Exclusion

  • Gadolinium Based Contrast Agent (other then Magnevist) enhanced MRI within 12 months prior to administration of Magnevist
  • History of NSF
  • Clinically unstable or age \<2 yrs

Key Trial Info

Start Date :

November 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2013

Estimated Enrollment :

168 Patients enrolled

Trial Details

Trial ID

NCT00744939

Start Date

November 1 2008

End Date

November 1 2013

Last Update

September 22 2014

Active Locations (26)

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Page 1 of 7 (26 locations)

1

Phoenix, Arizona, United States, 85008

2

Chula Vista, California, United States, 91910

3

Los Angeles, California, United States, 90033

4

Santa Rosa, California, United States, 95405