Status:
COMPLETED
Pre- and Intra-operative Intravitreal Bevacizumab Injection in Diabetic Vitrectomy
Lead Sponsor:
Seoul National University Bundang Hospital
Conditions:
Proliferative Diabetic Retinopathy
Vitreous Hemorrhage
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effect of pre- and intra-operative bevacizumab injection on postoperative vitreous hemorrhage after diabetic vitrectomy.
Detailed Description
Postoperative vitreous hemorrhage(VH) is a common complication after vitrectomy for proliferative diabetic retinopathy. Persistent or recurrent VH can delay visual rehabilitation and give patients muc...
Eligibility Criteria
Inclusion
- Patients undergoing first vitrectomy for complications of proliferative diabetic retinopathy such as vitreous hemorrhage, tractional fibrovascular membrane proliferation, tractional or combined retinal detachment)
Exclusion
- Follow-up period of less than 6 months
- Intraoperative use of long-acting gas or silicone oil
- Repeat vitrectomy after first vitrectomy for diseases other than vitreous hemorrhage
- Not first vitrectomy
- Uncontrolled hypertension
- Medical history of abnormal blood coagulation
- Time interval between IVB injection and PPV longer than 2 weeks and recent history (within 3 months) of IVB treatment
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
126 Patients enrolled
Trial Details
Trial ID
NCT00745498
Start Date
June 1 2008
End Date
October 1 2010
Last Update
December 21 2015
Active Locations (1)
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1
Seoul National University Bundang Hospital
Seongnam, Gyunggi-do, South Korea, 463-707