Status:
COMPLETED
Immediate Management of the Patient With Rupture : Open Versus Endovascular Repair
Lead Sponsor:
Imperial College London
Collaborating Sponsors:
London School of Hygiene and Tropical Medicine
University of Cambridge
Conditions:
Abdominal Aortic Aneurysm
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The purpose of this trial is to assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with sus...
Detailed Description
Rupture of the main blood vessel of the body in the abdomen (ruptured abdominal aortic aneurysm) is fatal in over three-quarters of cases. In the past, those that survive have reached hospital alive a...
Eligibility Criteria
Inclusion
- Clinical suspicion of ruptured abdominal aortic aneurysm after review in Accident and Emergency (or other hospital unit).
- Men and women over the age of 50 years will be recruited.
Exclusion
- Patients with known connective tissue disorders (eg Marfan syndrome) where endovascular repair may not be beneficial.
- Patients with known previous repair of an abdominal aortic aneurysm, because procedures either open or endovascular are likely to be very complex and there are no guidelines for anatomical restriction to repair.
- Deeply unconscious and moribund patients since the chances of recovery are minimal.
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 21 2016
Estimated Enrollment :
613 Patients enrolled
Trial Details
Trial ID
NCT00746122
Start Date
September 1 2009
End Date
July 21 2016
Last Update
December 19 2019
Active Locations (30)
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1
London Health Sciences Centre, University of Western Ontario
London, Ontario, Canada, N6A 5W9
2
Royal Cornwall Hospital
Truro, Cornwall, United Kingdom, TR1 3LJ
3
University Hospital of Wales, Cardiff and Vale NHS Trust
Cardiff, South Glamorgan, United Kingdom, CF14 4 XW
4
The Royal Wolverhampton Hospitals NHS Trust
Wolverhampton, West Midlands, United Kingdom, WV10 0QP