Status:
COMPLETED
Transfusion-Induced Alterations of Pulmonary and Immune Function in Mechanically Ventilated Patients
Lead Sponsor:
Mayo Clinic
Conditions:
Pulmonary Edemas
Blood Protein Disorders
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Specific aim: To test whether transfusion of leukoreduced red cells of lesser storage time (versus conventional storage time) reduces mild alterations in pulmonary function and immune activation in cr...
Detailed Description
Specific aim: To test whether transfusion of leukoreduced red cells of lesser storage time (versus conventional storage time) reduces mild alterations in pulmonary function and immune activation in cr...
Eligibility Criteria
Inclusion
- Patients, male or female, any race or ethnicity, age 18 years or older, in one of the seven adult critical care units of the Mayo Clinic, Rochester, with mechanically ventilated lungs, requiring elective transfusion of at least one unit of red cells
Exclusion
- transfusion of any blood component within the previous 2 hours, emergency transfusion or hemodynamic instability defined by other than a stable dose of vasoactive medications.
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2011
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00751322
Start Date
August 1 2008
End Date
December 1 2011
Last Update
January 31 2012
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905