Status:
UNKNOWN
Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis
Lead Sponsor:
Kwong Wah Hospital
Collaborating Sponsors:
The Hong Kong Society of Nephrology
Conditions:
Rate of Exit Site Infection
Rate of Atypical Mycobacterial Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Catheter-related infection, namely exit site infection and peritonitis, is the commonest complication of peritoneal dialysis. This complication causes significant morbidity and mortality in patients r...
Detailed Description
Topical antibiotics therapy is a well-recognized prophylactic therapy towards the catheter exit site infection in peritoneal dialysis patient. Previous data has shown the superiority of gentamicin cre...
Eligibility Criteria
Inclusion
- Patient aged 18 years old or above
- Patient has Tenckhoff catheter inserted
- Patient is expected to continue his or her dialysis in our center in the subsequent 3 years
Exclusion
- Patient fails to sign the written consent
- Patient known to have allergy to either gentamicin or mupirocin
- Patient has suffered from peritonitis or exit site infection 30 days before the enrollment.
- Patient, suffering from terminal illness, has life-expectancy of less than one year
- Patient expected to undergo peritoneal dialysis for less than one year, such as patients planning for elective renal transplantation or suffering from acute renal failure necessitating dialysis while waiting for the kidney to recover.
- Pregnant patient
- Patient known to be non-compliant
- Patient bound by another clinical study
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2014
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT00751374
Start Date
September 1 2008
End Date
October 1 2014
Last Update
September 11 2008
Active Locations (1)
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1
Kwong Wah Hospital
Hong Kong, Hong Kong