Status:

UNKNOWN

Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI)

Lead Sponsor:

University of Roma La Sapienza

Conditions:

Stable Angina

Percutaneous Coronary Intervention

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

Percutaneous coronary intervention (PCI) is associated with up to 30% incidence of myonecrosis, as reflected by elevation of cardiac enzymes in a successful procedure. Apart from side-branch occlusion...

Eligibility Criteria

Inclusion

  • Baseline creatine-kinase (CK) and creatine-kinase-myocardial band (CK-MB) had to be within normal limits (a normal CK and CK-MB and elevated troponin allowed inclusion)

Exclusion

  • Occlusion resulting in Thrombolysis In Myocardial Infarction (TIMI) grade 0 antegrade flow
  • Thrombus-laden lesions
  • Significant left main coronary stenosis
  • Left ventricular ejection fraction 30%
  • Inability to give informed consent
  • Bradycardia with heart rate below 50 b.p.m.
  • Allergy to adenosine
  • The occurrence of myo-cardial infarction within one week

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00751491

Start Date

September 1 2008

End Date

September 1 2009

Last Update

May 6 2009

Active Locations (1)

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Policlinico Umberto I

Rome, Italy, 00161