Status:

COMPLETED

A Study Comparing Ceramic-on-metal Articulation to Metal-on-metal Articulation in Cementless Primary Hip Arthroplasty

Lead Sponsor:

Zimmer Biomet

Conditions:

Osteoarthritis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this study is to demonstrate the non-inferiority of the ceramic on metal articulation using M2a-38™ mm cup compared to the metal on metal articulation using the same cup.

Detailed Description

The aim of this study is to demonstrate the non-inferiority of the ceramic on metal articulation using M2a-38™ mm cup compared to the metal on metal articulation using the same cup in regards to the c...

Eligibility Criteria

Inclusion

  • Patients presenting with osteoarthritis and suitable for primary Total Hip Replacement
  • Patients preoperative Harris Hip Score \<= 70 points
  • Patients aged over 18 and under 75
  • Patients with limited co-morbidity - ASA I-III
  • Patients with normal urea and electrolyte levels and creatinine levels
  • Patients must be able to understand instructions and be willing to return for follow-up
  • Patients willing to provide blood and urine samples for metal ion analysis at follow up

Exclusion

  • Patients preoperative Harris Hip Score \> 70 points
  • Previous prosthetic hip surgery
  • Patients with significant co-morbidity - ASA IV - V
  • Dementia and inability to understand and follow instructions
  • Neurological conditions affecting movement
  • Existing metal implant or fixation device
  • Pregnancy
  • Presence of symptomatic arthritis in other lower limb joints

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2021

Estimated Enrollment :

213 Patients enrolled

Trial Details

Trial ID

NCT00754520

Start Date

May 1 2009

End Date

December 1 2021

Last Update

October 2 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Central Finland Central Hospital

Jyväskylä, Finland

2

Kymenlaakso Central Hospital

Kotka, Finland

3

North Hampshire Hospital

Basingstoke, United Kingdom, RG24 9NA