Status:
COMPLETED
Structural and Functional Connectivity in Autism Spectrum Disorders
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
National Science and Technology Council, Taiwan
Conditions:
Autism Spectrum Disorder
Eligibility:
All Genders
3-15 years
Brief Summary
Autism spectrum disorder (ASD) has been given a high priority for genetic and neurobiological study. There is no such information in Asian population and no study has conducted using Diffusion Spectru...
Detailed Description
Autism spectrum disorder (ASD) is a pervasive neuro-developmental disorder with prominent reciprocal social and communication impairment and restricted repetitive behavior or interest. Because ASD run...
Eligibility Criteria
Inclusion
- The inclusion criteria for the subjects with ASD are:
- that subjects have a clinical diagnosis of autistic disorder, or Asperger disorder defined by the DSM-IV and ICD-10, which was made by a full-time board-certificated child psychiatrist at the first visit and following visits;
- their ages range from 3 to 15 when we conduct the study;
- subjects and their biological parents (and siblings if any) consent to participate in this study for completing clinical and brain imaging assessments and blood withdraw for genetic study (this criteria also applied to the controls).
Exclusion
- The proband subjects will be excluded from the study if they currently meet criteria or have a history of the following condition as defined by DSM-IV:
- Schizophrenia
- Schizoaffective Disorder
- Organic Psychosis
- severe neurological disease. Moreover, the subjects will also be excluded from the study if they completely cannot cooperate with MRI assessments.
Key Trial Info
Start Date :
January 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2012
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00755430
Start Date
January 1 2009
End Date
December 31 2012
Last Update
September 5 2021
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan