Status:

UNKNOWN

Treatment of Asymptomatic Toxocariasis With Albendazole in Children

Lead Sponsor:

Hospital de Niños R. Gutierrez de Buenos Aires

Conditions:

Toxocariasis

Eligibility:

All Genders

2-15 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate effectiveness of albendazole in the treatment of the asymptomatic infection with the parasite Toxocara in children. Treatment response is defined as a reductio...

Eligibility Criteria

Inclusion

  • Pediatric ambulatory patients with asymptomatic toxocariasis
  • Children 2 - 15 years old
  • Absolute eosinophil count \> 1100 / mm3
  • Normal ophthalmoscopy

Exclusion

  • Treatment with a benzimidazole in the previous year
  • Infection by other nematodes (Ascaris lumbricoides, strongyloides stercoralis, uncinarias, Trichuris trichuria)
  • Symptomatic patients (prolonged fever, acute pneumonitis, hepatomegaly, splenomegaly, ocular compromise due to toxocara)
  • Concomitant diseases
  • Immunocompromised patients
  • Altered liver or kidney function
  • Pregnancy

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2025

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT00755560

Start Date

September 1 2008

End Date

July 1 2025

Last Update

March 2 2023

Active Locations (1)

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Parasitology Division, Children's Hospital "R Gutierrez" of Buenos Aires

Buenos Aires, Argentina, 1425