Status:
COMPLETED
Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
Pfizer
Conditions:
Arrhythmia
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine if atorvastatin (Lipitor) reduces the occurence of abnormal heart rhythm (atrial arrhythmia) following non cardiac thoracic surgery.
Detailed Description
The incidence of atrial arrhythmia after thoracic, non-cardiac procedures is exceedingly common and has been reported to occur in between 10-39% of patients. It has been shown to increase majority mor...
Eligibility Criteria
Inclusion
- Patients scheduled for elective non-cardiac thoracic surgery requiring thoracotomy for resection
Exclusion
- Past medical history of pacemaker implantation
- Pregnancy or lactating
- History of Atrial arrhythmia within the past year
- Elevated liver enzymes pre-operatively
- Past medical history of any liver disease or history of liver transplantation
- Use of statins or any anti-arrhythmics (including beta-blockers, calcium channel blockers, digoxin) within 3 months prior to surgery
- Pre-op EKG showing atrial arrhythmia
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2011
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT00756886
Start Date
September 1 2008
End Date
May 1 2011
Last Update
April 2 2013
Active Locations (1)
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1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294