Status:

COMPLETED

Intraoperative Gamma Camera for Breast Cancer Surgery

Lead Sponsor:

University Hospital, Strasbourg, France

Collaborating Sponsors:

Institut Pluridisciplinaire Hubert Curien. UMR 7178 - CNRS/IN2P3

ULP. F-67037 Strasbourg

Conditions:

Breast Cancer

Ductal Carcinoma in Situ

Eligibility:

FEMALE

18+ years

Phase:

PHASE3

Brief Summary

Aim: This study aims at evaluating the performances of an intraoperative gamma camera (field of view 10X10 cm), named CarolIReS, to detect axillary drainage and to assess the removal of sentinel lymph...

Detailed Description

Group I : The SLN procedure will be initiated 18 hours before surgery using a preoperative injection of colloidal rhenium sulphur and technetium (0.4 ml, 20 MBq of Nanocis®; CIS Bio International, Fra...

Eligibility Criteria

Inclusion

  • Patient major at the time of breast surgery.
  • Patient affiliated with a social security.
  • Consent dated and signed by the investigator and the subject.
  • Subject having been informed of the sentinel lymph node procedure during the visit prior to breast surgery.
  • Patient having a unifocal infiltrative breast cancer (less than 2 cm) diagnosed preoperatively by core biopsy or cytology.
  • Patient having a ductal carcinoma in situ (DCIS), diagnosed preoperatively by core biopsy or cytology.

Exclusion

  • Refusal of the patient to be included in the study.
  • Pregnant patient or during breastfeeding.
  • None of the patients will have undergone chemotherapy, locoregional radiotherapy or prevalent axillary lymph node.
  • Diagnosed safeguarding justice and trust.
  • Patient with a psychiatric disorder makes it impossible for the collection of informed consent-patient with tumors greater than 2 cm or multifocal.
  • Prevalent axillary lymph node.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2014

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT00757302

Start Date

September 1 2008

End Date

September 1 2014

Last Update

December 22 2025

Active Locations (1)

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CHRU, Hôpital Civil ,Service de Gynécologie-obstétrique

Strasbourg, France, 67091