Status:

COMPLETED

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis

Lead Sponsor:

AstraZeneca

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

16+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to investigate if treatment with AZD9668 for 28 days is effective in treating Cystic Fibrosis (CF) and if so how it compares to placebo (a substance which does not have an...

Eligibility Criteria

Inclusion

  • Male or post-menopausal or surgically sterile female patients
  • Have a clinical diagnosis of Cystic Fibrosis with lung function tests greater or equal to 40% of normal
  • Have normal renal function

Exclusion

  • Lung transplant patients
  • Significant liver disease
  • Any other non-CF-related lung disease that may interfere with study assessments

Key Trial Info

Start Date :

October 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2009

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT00757848

Start Date

October 1 2008

End Date

August 1 2009

Last Update

August 20 2012

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Research Site

Copenhagen, Denmark

2

Research Site

Hamburg, Germany

3

Research Site

Kiel, Germany

4

Research Site

Leipzig, Germany