Status:

COMPLETED

Evaluate Effectiveness of the Biomet Lumbar Spinal Fusion System

Lead Sponsor:

Zimmer Biomet

Conditions:

Degenerative Disc Disease

Eligibility:

All Genders

18-75 years

Brief Summary

The purpose of this study is to evaluate the effectiveness of the Biomet Lumbar Spinal Fusion System in patients undergoing lumbar fusion surgery.

Detailed Description

All subjects enrolled in this study will receive the The Biomet Osteobiologic Treatment System which is comprised of the SpF® Spine Fusion Stimulator and any or all of the following can be utilized in...

Eligibility Criteria

Inclusion

  • The subject must, in the investigator's opinion, be psychosocially, mentally, and physically able to fully comply with this protocol including the required follow-up visits, the filling out of required forms, and have the ability to understand and give written informed consent.
  • The subject must be diagnosed with degenerative disc disease at up to 2 levels from L2-S1 inclusive and undergoing up to 2 level posterior lumbar spinal fusion surgery with or without anterior column fusion.
  • Subjects must be between 18 and 75 years of age.
  • The patient must be skeletally mature (epiphyses closed).

Exclusion

  • Subject is pregnant, lactating or interested in becoming pregnant during the duration of the study.
  • Any active litigation.
  • Subject is currently involved in another investigational study.
  • Subject has a history (present or past) of substance abuse (recreational drugs, prescription drugs or alcohol) that in the investigator's opinion may interfere with protocol assessments and/or with the subject's ability to complete the protocol required follow-up.
  • Subject is incarcerated.
  • More than 2 prior spine surgeries/revision surgeries or any previous spinal fusions at levels being currently treated.
  • Traumatic instability.
  • Any parathyroid or metabolic bone disease.
  • Any active malignancy.
  • Osteopenia/Osteoporosis - All subjects will be screened for osteoporosis using SCORE (Simple Calculated Osteoporosis Risk Estimation) with a threshold value of 6. All subjects with a SCORE value greater than 6 will be referred for Dual-energy X-ray absorptiometry (DEXA) Scan. Subjects with a T-Score of £-1-2.5 will be excluded.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2012

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT00758719

Start Date

September 1 2008

End Date

August 1 2012

Last Update

February 24 2020

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Union Hospital Neurosurgical

Terre Haute, Indiana, United States, 47807

2

Family Orthopedic Associates

Flint, Michigan, United States, 48507

3

Orthopedics and Neurological Consultants, Inc

Columbus, Ohio, United States, 43212

4

Neurological Associates of Waukesha

Waukesha, Wisconsin, United States, 53188