Status:

TERMINATED

Metabolomic Profiling of Novel Mediators of Vascular Function

Lead Sponsor:

Brigham and Women's Hospital

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to identify and characterize specific chemicals and metabolic pathways that change with forearm ischemia. These changes will be compared with forearm blood flow and flow-m...

Eligibility Criteria

Inclusion

  • Adults age 18 or older
  • Type 2 diabetes mellitus

Exclusion

  • Type 1 diabetes mellitus
  • Type 2 diabetics taking insulin, thiazolidinediones (rosiglitazone or pioglitazone), an amylin analog (Symlin \[pramlintide\]), or incretin mimetics (Byetta \[exenatide\])
  • Pregnancy
  • Uncontrolled hypertension, \> 180/100 mmHg

Key Trial Info

Start Date :

May 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 1 2018

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT00762242

Start Date

May 1 2007

End Date

February 1 2018

Last Update

December 12 2016

Active Locations (1)

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Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115