Status:

COMPLETED

Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)

Lead Sponsor:

AbbVie (prior sponsor, Abbott)

Conditions:

Chronic Low Back Pain

Eligibility:

All Genders

21-75 years

Phase:

PHASE3

Brief Summary

The primary purpose of the study is to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanica...

Detailed Description

The study used a randomized withdrawal design with an open label (OL) period prior to a double-blind (DB) period. Participants who were receiving benefit and were tolerating ABT-712 during the OL peri...

Eligibility Criteria

Inclusion

  • Adult male and female subjects who voluntarily sign the informed consent
  • Diagnosis of CLBP of 6 months duration

Exclusion

  • Incapacitated or bedridden subjects
  • Subjects with history of surgical or invasive intervention

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2009

Estimated Enrollment :

287 Patients enrolled

Trial Details

Trial ID

NCT00763321

Start Date

September 1 2008

End Date

April 1 2009

Last Update

February 6 2014

Active Locations (31)

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Page 1 of 8 (31 locations)

1

Site Reference ID/Investigator# 10044

Huntsville, Alabama, United States, 35801

2

Site Reference ID/Investigator# 10070

Burbank, California, United States, 91505

3

Site Reference ID/Investigator# 10050

San Diego, California, United States, 92108

4

Site Reference ID/Investigator# 10060

Atlantis, Florida, United States, 33462