Status:

COMPLETED

Phase II Study of Safety and Feasibility of Intensive Blood Glucose Control With Insulin on Acute Medical Wards

Lead Sponsor:

St George's, University of London

Conditions:

COPD

Hyperglycemia

Eligibility:

All Genders

40+ years

Phase:

PHASE2

Brief Summary

Patients with chronic obstructive pulmonary disease (COPD) are commonly admitted to hospital with exacerbations of their lung disease. A combination of the acute illness and treatment with oral steroi...

Eligibility Criteria

Inclusion

  • Physician diagnosis of AECOPD as primary cause for admission
  • Able to enter study within 24 hours of admission

Exclusion

  • Intensive care unit admission
  • Moribund or not for active treatment
  • Admission expected to last \<48 hours
  • Unable or unwilling to give informed consent
  • Known Type I diabetes mellitus
  • Patients with reduced awareness of hypoglycaemia including reduced Glasgow coma scale or those taking beta blockers
  • Patients with renal or hepatic failure at increased risk of hypoglycaemia

Key Trial Info

Start Date :

May 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2009

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00764556

Start Date

May 1 2008

End Date

May 1 2009

Last Update

October 14 2009

Active Locations (1)

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1

St George's Healthcare NHS Trust

London, United Kingdom, SW17 0RE