Status:
COMPLETED
The Effect of Neuromuscular Electrical Stimulation (NMES)
Lead Sponsor:
University of Pittsburgh
Conditions:
Muscle Fiber Atrophy, Type II
Eligibility:
All Genders
65-80 years
Phase:
PHASE2
Brief Summary
The purpose of this project is to test the effectiveness of neuromuscular electrical stimulation (NMES) that produces 40 % of maximum voluntary contraction (MVC) in increasing muscle size and improvem...
Detailed Description
Declines in whole skeletal muscle strength and size are features commonly associated with aging. Aging reduces the number of fibers in the whole muscle, which explains the loss of muscle mass. Fronter...
Eligibility Criteria
Inclusion
- 65-80 years old, are walking independently without assistive devices.
Exclusion
- Uncontrolled hypertension (defined as the following: 1) if not taking BP medication and resting systolic BP is greater than 140 or diastolic greater than 90, or 2) if taking BP medication and resting systolic BP greater than 160 or diastolic greater than 100).
- History of cardiovascular disease
- History of neurological disorders that effect lower extremity function (stroke, peripheral neuropathy, Parkinson's disease, multiple sclerosis)
- One cortico-steroid injection to the quadriceps or patellar tendon in the past month or 3 within the past year.
- History of quadriceps tendon rupture, patellar tendon rupture, or patellar fracture, which could place them at risk of re-injury during quadriceps strength testing.
- Current pain in the knee or in the thigh muscles.
- Diagnosis of inflammatory arthritis (Rheumatoid arthritis, gout, or psoriatic arthritis)
- Muscle diseases such as muscular dystrophy.
- Currently been participating in a regular exercise program more than 1x/week.
- Been using anticoagulants and platelet inhibitors
- History of chronic and significant respiratory disease or shortness of breath
- Visual impairments to the extent that they can not accurately see the monitor screen during training program.
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT00765739
Start Date
October 1 2008
End Date
August 1 2012
Last Update
January 24 2013
Active Locations (1)
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1
School of Health and Rehabilitation Sciences
Pittsburgh, Pennsylvania, United States, 15260