Status:
TERMINATED
Osteoarthritis and Body Composition: Evaluation of Systematic Mediators
Lead Sponsor:
National Institute on Aging (NIA)
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
20+ years
Brief Summary
The purpose of this study is to examine the relationship between body composition and knee osteoarthritis, and effects of inflammatory, metabolic, and hormonal factors.
Detailed Description
Banked serum and urine specimens obtained from NIA Baltimore Longitudinal Study on Aging (BLSA) participants with and without knee OA will be used to determine inflammatory, metabolic, bone and joint ...
Eligibility Criteria
Inclusion
- Participants of the BLSA who have had 1 or more DXA scans AND who were either classified as having radiographic knee OA (Kellgren \& Lawrence 2 or higher) or as having no radiographic knee OA on two or more xrays (KL 0-1)
Exclusion
- Diagnosis of rheumatoid arthritis
- Diagnosis of malignancy
- Reported use of prednisone and other immunosuppressive medications or insulin
Key Trial Info
Start Date :
January 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
1033 Patients enrolled
Trial Details
Trial ID
NCT00771082
Start Date
January 1 2003
End Date
December 1 2012
Last Update
June 6 2012
Active Locations (1)
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1
National Institute on Aging
Baltimore, Maryland, United States, 21225