Status:
UNKNOWN
Oxidative Stress and Microcirculation in Patient With Hepatic Failure Undergoing Liver Support Treatment
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Liver Failure
Critical Care
Eligibility:
All Genders
18-70 years
Brief Summary
Background: In patients undergoing hemodialysis or hemofiltration will suffer from the injury of reactive oxidative species. Oxidative stress will affect cell membrane, protein, and DNA. It will damag...
Eligibility Criteria
Inclusion
- Age \> 18 years old
- Patients with acute deterioration on Chronic liver failure, who required liver support treamtment
- Patients with acute liver failure due to acute hepatitis, who reauired liver support treatment
- Patients with acute liver dysfunction within 7 days after liver transplantation, who required liver support treatment
Exclusion
- Age \> 70 years old
- Cancer, not curable
- Patients who had used of antioxidant therapy within 24 hours before study
- Patients who had received hyperbaric oxygen therapy within 24 hours before study
- Patients who had received peroxide treatment within 24 hours before study
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2010
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00772252
Start Date
August 1 2008
End Date
December 1 2010
Last Update
June 29 2010
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100