Status:
WITHDRAWN
Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)
Lead Sponsor:
Ochsner Health System
Conditions:
Postoperative Nausea and Vomiting
Eligibility:
FEMALE
18-65 years
Phase:
NA
Brief Summary
The purpose of this study is to see if the nicotine patch reduces post operative nausea and/or vomiting (PONV) among non-smoking patients who are at high risk of PONV.
Detailed Description
There are certain known risk factors for post-operative nausea and/or vomiting: the use of opioids during surgery, female gender, laparoscopic surgery, gynecologic surgery, strabismus repair, the use ...
Eligibility Criteria
Inclusion
- age 18-65
- female
- health patient or acute illness
- undergoing outpatient-type general surgery, especially those associated with increased incidence of post-operative nausea and/or vomiting such as gynecological procedures
- undergoing general anesthesia for the surgery
- receiving opioids during surgery
- non-smokers
Exclusion
- history of any heart condition
- history of uncontrolled hypertension, or presence of any condition that could be made drastically worse by an increase in blood pressure
- history of an aneurysm
- active tobacco use within the past five years
- works or lives in the presence of cigarette smoke
- pregnant
- mentally ill
- prisoners
- history of allergic reaction to nicotine or to adhesive patches
- history of allergic reaction to propofol, versed, fentanyl, zofran, decadron, and reglan
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00775749
Start Date
April 1 2009
End Date
April 1 2012
Last Update
April 11 2023
Active Locations (1)
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1
Ochsner Clinic Foundation
New Orleans, Louisiana, United States, 70121