Status:
COMPLETED
T-Cat Laser & Cross-linking for Keratoconus
Lead Sponsor:
Moorfields Eye Hospital NHS Foundation Trust
Collaborating Sponsors:
Accuvision Laser Eye Clinics
Carleton Optical Equipment Ltd.
Conditions:
Keratoconus
Pellucid Marginal Degeneration
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether excimer laser corneal surface ablation (T-Cat) can be safely combined with simultaneous corneal collagen cross-linking treatment to produce an improve...
Detailed Description
Theoretical framework: Corneal ectasia is a relative weakness in the structure of the cornea, which produces a progressive change in its shape with resultant visual distortion. Excimer laser surface...
Eligibility Criteria
Inclusion
- Patients with known keratoconus or pellucid marginal degeneration.
Exclusion
- Age \< 18 years \> 50 years.
- Minimal corneal pachymetry in eye to be treated of \< 400μ.
- Evidence of other corneal disease in the eye to be treated (e.g. Herpes simplex keratitis).
- Women who are pregnant or nursing at the time of the initial treatment.
- Presence of significant central corneal opacity.
- Patients unwilling to not wear rigid contact lenses in the eye to be operated on for at least one month before baseline examination, and for the first six months post-operatively.
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00777322
Start Date
October 1 2008
End Date
October 1 2010
Last Update
July 21 2011
Active Locations (1)
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1
Moorfields Eye Department at St George's Hospital
London, London, United Kingdom, SW17 0QT