Status:

TERMINATED

Study Using Dexmedetomidine to Decreases Emergence Delirium in Pediatric Patients

Lead Sponsor:

Ochsner Health System

Conditions:

Otitis Media

Eligibility:

All Genders

1-5 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the use of intranasal dexmedetomidine to reduce the incidence of emergence delirium during general sevoflurane anesthesia in a pediatric population receiving p...

Detailed Description

Emergence delirium has been described as a dissociated state of consciousness in which the child is irritable, uncompromising, uncooperative, incoherent, inconsolably crying, moaning, kicking or thras...

Eligibility Criteria

Inclusion

  • ASA class 1 or 2 (healthy patient or acute illness)
  • Parental willingness to participate
  • Candidate for pressure-equalization tubes (PET) as determined by the ENT department

Exclusion

  • ASA class 3 or 4 (chronic illness or life-threatening illness)
  • Parental refusal to participate
  • Significant liver disease by history
  • Allergy to dexmedetomidine or midazolam
  • Nasal deformity
  • Fever in the three days prior to surgery
  • Nausea or vomiting
  • History of hypertension
  • History of cardiac dysfunction/disorder
  • Diabetes mellitus

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2013

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00778063

Start Date

September 1 2008

End Date

March 1 2013

Last Update

April 13 2023

Active Locations (1)

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1

Ochsner Clinic Foundation

New Orleans, Louisiana, United States, 70121