Status:
TERMINATED
Anesthesic Propofol and Remifentanil Requirements in Obese Patients
Lead Sponsor:
Hopital Foch
Conditions:
Anesthesia
Obesity
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Pharmacokinetic models for anesthetic agents are questionable. The objective of the study is to compare the propofol and remifentanil doses required to maintain the bispectral index in the range 40-60...
Eligibility Criteria
Inclusion
- \- Patients scheduled for a bariatric coelioscopic surgical procedure (obese patients) or for an upper abdominal laparoscopic procedure (lean patients)
Exclusion
- age lower than 18 years,
- pregnant woman,
- presence of a central neurological disorder or a lesion cerebral, of a severe respiratory or hepatic insufficiency,
- allergy to propofol, or to soja or to peanuts, or to sufentanil, or to remifentanil, or to morphine, or to a muscle myorelaxant, or to an excipient,
- hypersensibility to sufentanil, or to remifentanil or to another derivate of fentanyl,
- allergy to latex,
- presence of a symptomatic gastroesophageal reflux,
- patients receiving a psychotropic treatment or a agonist-antagonist opiate,
- presence of predictive signs of difficult mask ventilation of difficult intubation (else than obesity)
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT00779844
Start Date
December 1 2008
End Date
December 1 2012
Last Update
September 23 2016
Active Locations (1)
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1
Hôpital Européen Georges Pompidou
Paris, France, 75015