Status:
UNKNOWN
Determinants of Insulin-induced Weight Gain in Type 2 Diabetes Mellitus
Lead Sponsor:
Radboud University Medical Center
Conditions:
Type 2 Diabetes Mellitus
Weight Gain
Eligibility:
All Genders
18-85 years
Brief Summary
The purpose of this study is to find determinants of insulin-induced weight gain in type 2 diabetes mellitus Primary objective: To find an association between weight gain after start of insulin thera...
Detailed Description
Insulin therapy is frequently needed to achieve adequate glycaemic control in type 2 diabetes mellitus (T2DM), but often at the expense of weight gain. Insulin-induced weight gain is obviously undesir...
Eligibility Criteria
Inclusion
- patients with type 2 diabetes mellitus
- age 18-85 years
- Hba1c at baseline \< 12.0%
- written informed consent
Exclusion
- Clinical evidence of psychiatric, renal, cardiovascular or liver or other diseases which may influence study results regarding glucose and weight
- Patients with hormonal disorders which may influence weight (i.e. thyroid diseases), even if properly treated with stable hormonal levels
- Excessive alcohol consumption (\>20 g/day), and drug abuse
- Use of thiazolidinedione derivatives (TZDs)
- Pregnancy or intention to become pregnant during the study
Key Trial Info
Start Date :
December 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2011
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00781495
Start Date
December 1 2008
End Date
December 1 2011
Last Update
July 12 2011
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Radboud University Nijmegen Medical Centre
Nijmegen, Gelderland, Netherlands, 6500 HB
2
Jeroen Bosch Hospital
's-Hertogenbosch, North Brabant, Netherlands, 3400 NL
3
Jeroen Bosch Hospital
's-Hertogenbosch, North Brabant, Netherlands