Status:
COMPLETED
Influenza Vaccination in Immunocompromized Patients
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Collaborating Sponsors:
Boehringer Ingelheim
Abbott
Conditions:
Immunosuppression
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Evaluation of the immunogenicity and reactogenicity of two different formulations of commercially avail-able influenza vaccines in 4 different groups of immunocompromized outpatients (HIV positive pat...
Detailed Description
The infection with influenza is associated with higher morbidity and mortality in risk groups including immunocompromized patients. The virosomal influenza vaccines have been associated with improved ...
Eligibility Criteria
Inclusion
- Adult outpatients treated at the Inselspital Bern for:
- HIV infection
- rheumatologic diseases and receiving immunosuppressive drugs
- kidney transplant recipients
- undergoing hemodialysis or continuous ambulatory peritoneal dialysis
- written informed consent
Exclusion
- Allergy to egg proteins
- Former adverse reactions to prior vaccination
- Febrile conditions at the time of study inclusion
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2008
Estimated Enrollment :
304 Patients enrolled
Trial Details
Trial ID
NCT00783380
Start Date
October 1 2005
End Date
March 1 2008
Last Update
November 3 2008
Active Locations (3)
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1
Department of Infectious Diseases, Bern University Hospital
Bern, Switzerland, 3010
2
Department of Nephrology/Hypertension, Bern University Hospital
Bern, Switzerland, 3010
3
Department of Rheumatic Diseases, Bern University Hospital
Bern, Switzerland, 3010