Status:
UNKNOWN
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Lead Sponsor:
Universidad Nacional de Córdoba
Collaborating Sponsors:
Fundación Florencio Fiorini
Conditions:
Polycystic Ovary Syndrome
Eligibility:
FEMALE
18-35 years
Brief Summary
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population. In 2003 a committee o...
Detailed Description
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population. Its cause remains no...
Eligibility Criteria
Inclusion
- Two of the following
- Ovulatory Dysfunction: Clinically defined by oligomenorrhea (menstrual cycles lasting more than 35 days) or amenorrhea (lacking of menstruations in the last 90 days). In patients with menstrual cycles between 25 and 35 days, a serum level of progesterone drawn during days 21 to 23 of cycle \< a 4 ng/ml.
- Clinical hyperandrogenism defined for the presence of hirsutism, acne, androgenic alopecia) and or biochemical (increases in total testosterone, bioavailable testosterone or free androgen index).
- Polycystic Ovaries: Defined by the presence, in as less one ovary, of 12 or more follicles (measuring 2 to 9 mm in diameter) and or increased ovarian volume \> 10 mL).
Exclusion
- Hyperprolactinemia
- Hypothyroidism
- Other causes of hyperandrogenism like Cushing's Syndrome, congenital adrenal hyperplasia, androgens secreting tumors
- Drug therapy used three months previous to enrollment in the study
Key Trial Info
Start Date :
December 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00784615
Start Date
December 1 2007
Last Update
November 19 2008
Active Locations (1)
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1
Hospital Universitario de Maternidad y Neonatología
Córdoba, Córdoba Province, Argentina, X5000