Status:
COMPLETED
Study of New Biological Markers for Prediction of Severe Acute Pancreatitis
Lead Sponsor:
National University Hospital, Singapore
Collaborating Sponsors:
National University of Singapore
National Medical Research Council (NMRC), Singapore
Conditions:
Acute Pancreatitis
Eligibility:
All Genders
18+ years
Brief Summary
Acute pancreatitis refers to inflammation of the pancreas and is associated with sudden onset of severe abdominal pain, often accompanied by transient systemic manifestations, including fever. In the ...
Eligibility Criteria
Inclusion
- The patient should fulfill all of the following criteria:
- The subject should be at least 18 years of age.
- Clinical features compatible with acute pancreatitis.
- First symptoms of acute pancreatitis not more than 72 hours before enrolment.
- Serum amylase level above 480 U/dl (normal 60-160 U/dl or 2-hour urinary amylase greater than 1120 U (normal 280 U).
- Serum lipase levels greater than 2 U (normal \< 1 U).
- Patient has signed consent form regarding participation in the study.
Exclusion
- The patient should not present any of the following criteria:
- Symptoms of acute pancreatitis present for more than 72 hours
- Clinical evidence of sepsis or other inflammatory diseases.
- Clinical evidence of disorders/disease known to affect endogenous regulation of substance P, e.g. asthma, immune-complex-mediated lung injury, arthritis.
- Age under 18 years
- Pregnancy
Key Trial Info
Start Date :
June 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT00786591
Start Date
June 1 2006
End Date
July 1 2009
Last Update
December 31 2012
Active Locations (1)
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1
National University Hospital
Singapore, Singapore, 119074