Status:

COMPLETED

Heliox in Experimental Upper Airway Obstruction

Lead Sponsor:

University of Witten/Herdecke

Conditions:

Airway Obstruction

Dyspnea

Eligibility:

All Genders

18-60 years

Phase:

PHASE1

PHASE2

Brief Summary

Currently it is common medical wisdom that HELIOX (mixture of Helium in Oxygen) with a fraction of Helium below 60% is not effective in reducing airway obstruction. The investigators test the hypothes...

Detailed Description

HELIOX is a mixture of Helium and Oxygen. It is a therapeutic modality that can improve upper and lower airway obstruction. The lower density of Helium can help to relieve airway obstruction and is kn...

Eligibility Criteria

Inclusion

  • Volunteers of both sexes were recruited via posting in student forum of University of Witten/Herdecke
  • Willingness to spend about 2h in the clinical exp. lab.

Exclusion

  • Acute airway infection
  • History of asthma
  • Smokers
  • Pregnancy
  • Abnormal lab. screen with liver function tests, Creat./BUN, CBC, blood glucose
  • Anxiety or mood disorder
  • Any chronic disease (incl. lung \& heart disease, cancer, endocrine disorder)
  • Mental retardation

Key Trial Info

Start Date :

November 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT00788788

Start Date

November 1 2007

Last Update

November 21 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

HELIOS-Klinikum / University of Witten/Herdecke

Wuppertal, North Rhine-Westphalia, Germany, 42283