Status:

COMPLETED

An Open-label Study of Vedolizumab (MLN0002) in Participants With Ulcerative Colitis and Crohn's Disease

Lead Sponsor:

Takeda

Conditions:

Ulcerative Colitis

Crohn's Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this multicenter, open-label study is to collect data on the occurrence of important clinical safety events resulting from chronic vedolizumab (MLN0002) administration.

Detailed Description

The drug being tested in this study is called vedolizumab. Vedolizumab is being tested to treat people who have ulcerative colitis or Crohn's disease. This study will determine the safety profile of l...

Eligibility Criteria

Inclusion

  • Previous treatment in Study C13004 (NCT00619489), Study C13006 (NCT00783718), Study C13007 (NCT00783692), or Study C13011 (NCT01224171) that, in the opinion of the investigator, was well tolerated OR b. Moderate to severe Crohn's disease or ulcerative colitis which has not been previously treated with vedolizumab (MLN0002)
  • May be receiving a therapeutic dose of conventional therapies for Crohn's disease or ulcerative colitis as defined by the protocol

Exclusion

  • 1\. Development of any new, unstable, or uncontrolled disease

Key Trial Info

Start Date :

May 22 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2017

Estimated Enrollment :

2243 Patients enrolled

Trial Details

Trial ID

NCT00790933

Start Date

May 22 2009

End Date

October 31 2017

Last Update

May 24 2022

Active Locations (41)

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Page 1 of 11 (41 locations)

1

Birmingham, Alabama, United States, 35233

2

San Diego, California, United States, 92114

3

San Francisco, California, United States, 94115

4

Lafayette, Colorado, United States, 80026