Status:

COMPLETED

Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development

Lead Sponsor:

Wageningen University

Collaborating Sponsors:

St. John's Research Institute

Mahidol University

Conditions:

Iodine Deficiency

Infant Development

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

Rationale: In regions of severe endemic goiter, the adverse effects of in utero iodine deficiency on neuromotor development are well established: randomized controlled trials of iodine supplements giv...

Eligibility Criteria

Inclusion

  • Age 18-40 years;
  • Gestational age: ≤ 14 weeks (as judged by the date of the last menstrual period);
  • Single pregnancy;
  • Non-lactating;
  • Planned residence in the area for the duration of the study (3 years).

Exclusion

  • TSH levels outside the normal range
  • History of serious medical conditions such as HIV, hypertension, diabetes, renal, hepatic or cardiovascular disease, thyroid disorders, mental disorders;
  • Use of iodine supplement.

Key Trial Info

Start Date :

September 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2016

Estimated Enrollment :

829 Patients enrolled

Trial Details

Trial ID

NCT00791466

Start Date

September 1 2008

End Date

May 1 2016

Last Update

November 21 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

St. Johns Medical College and Research Institute

Bangalore, India, 560034

2

Insitute of Nutrition, Mahidol University (INMU)

Bangkok, Thailand, 73170