Status:
COMPLETED
Management of Nausea and Vomiting of Pregnancy
Lead Sponsor:
University College Cork
Conditions:
Hyperemesis Gravidarum
Nausea
Eligibility:
FEMALE
Phase:
NA
Brief Summary
Upto 80% of all pregnant women experience some form of nausea and vomiting (NVP) during their pregnancy. Hyperemesis gravidarum, a more severe form of NVP affects approximately 0.3- 2.0% of pregnancie...
Detailed Description
Upto 80% of all pregnant women experience some form of nausea and vomiting during their pregnancy (NVP). The International Statistical Classification of Disease and Related Health Problems ICD-10 defi...
Eligibility Criteria
Inclusion
- Women (no age limits) will be admitted to the study if they have two or more of the following criteria
- Ongoing viable intrauterine pregnancy/ pregnancies \< 22 weeks gestation
- Persistent vomiting (\>x3 episodes/ 24 hours) not attributable to other causes
- Severe nausea not attributable to other causes.
- Dehydration diagnosed by the presence of ketonuria.
- Electrolyte imbalance not attributable to other causes.
Exclusion
- Women will not be admitted to the study if any of the following criteria are present.
- Women with a confirmed urinary tract infection (mid stream urine isolation of a single strain of uropathogen \>105 bacteria/ml)
- Women with molar pregnancies
- Women with non viable pregnancies.
- Women who have already received treatment for NVP outside of this trial.
- Pregnant women who present who will not be booking at CUMH for their pregnancy or are not resident in the South West of Ireland i.e. day care treatment is not an option.
- Women who do not have a good understanding of English.
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT00795561
Start Date
April 1 2009
End Date
September 1 2012
Last Update
January 15 2014
Active Locations (1)
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1
Department of Obstetrics and Gynaecology, Cork University Maternity Hospital
Cork, Ireland