Status:
TERMINATED
Comparison of 2 Doses of Mannitol on Post Traumatic Intracranial Hypertension and Cerebral Monitoring
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Traumatic Brain Injury
Intracranial Hypertension
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
Will an increase of the dose of mannitol improve the effects on neuromonitoring in patients suffering intracranial hypertension following traumatic brain injury?
Detailed Description
traumatic brain injury intracranial hypertension 0,4 g/ kg vs 0,8 g/ kg (randomized) on 20 minutes monitoring: ICP, transcranial doppler, brain pO2, MAP, HR, diuresis, biology duration: 2 hours
Eligibility Criteria
Inclusion
- adults
- severe traumatic brain injury
- intracranial hypertension requiring mannitol administration
Exclusion
- impeding neurosurgery
- hemodynamic or respiratory severe failure
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT00795587
Start Date
October 1 2008
End Date
August 1 2011
Last Update
November 8 2012
Active Locations (1)
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1
Universitary Hospital
Grenoble, France, 38043